Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 18/20 | 0.69 |
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.69 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821750 | 0.91 | LTB4R (0.72) | LTB4RLTB4R2 | |
| SCHEMBL5183040 | 0.91 | LTB4R (0.83) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8957196 | 0.90 | LTB4R (0.73) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821707 | 0.89 | LTB4R (0.79) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL10838006 | 0.86 | LTB4R (0.62) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL10633788 | 0.86 | LTB4R (0.70) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9201186 | 0.85 | LTB4R (0.74) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8957078 | 0.85 | LTB4R (0.76) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821777 | 0.84 | LTB4R (0.62) | LTB4RLTB4R2 | |
| SCHEMBL8957123 | 0.84 | LTB4R (0.61) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292977-B1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLATE DERIVATIVES | G.D. Searle & Co. (US) | 1991-09-04 | — | — | EP | disclosed |
| US-4889871-A | ANTIINFLAMMATORY AGENTS; SELECTIVE LEUKOTRIENE ANTAGONISTS | G. D. SEARLE & CO. (US) | 1989-12-26 | — | — | US | disclosed |