Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.67 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.67 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821815 | 0.90 | LTB4R (0.74) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL11009012 | 0.90 | LTB4R (0.78) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821682 | 0.88 | LTB4R (0.71) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL11012752 | 0.88 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821676 | 0.88 | LTB4R (0.86) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821669 | 0.87 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821799 | 0.85 | LTB4R (0.74) | LTB4RLTB4R2 | |
| SCHEMBL9193321 | 0.85 | LTB4R (0.61) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL10702506 | 0.84 | LTB4R (0.65) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL10704583 | 0.84 | CYSLTR1 (0.75) | LTB4RLTB4R2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292977-B1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLATE DERIVATIVES | G.D. Searle & Co. (US) | 1991-09-04 | — | — | EP | claimed |