Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 11/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821758 | 0.93 | LTB4R (0.53) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821770 | 0.88 | LTB4R (0.42) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821665 | 0.86 | LTB4R (0.50) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821686 | 0.85 | LTB4R (0.44) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821690 | 0.85 | LTB4R (0.44) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821820 | 0.85 | LTB4R (0.44) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| Sc-39070 SCHEMBL9119171 | 0.83 | CYSLTR2 (0.56) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821874 | 0.83 | LTB4R (0.52) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821736 | 0.82 | LTB4R (0.51) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL10407892 | 0.80 | CYSLTR2 (0.58) | LTB4RLTB4R2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292977-B1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLATE DERIVATIVES | G.D. Searle & Co. (US) | 1991-09-04 | — | — | EP | disclosed |
| EP-0292977-A1 | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives | G.D. Searle & Co. (US) | 1988-11-30 | — | — | EP | disclosed |