Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.76 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.62 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.60 |
| ▸ | CTSL | P07711 | 3/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | CTSK | P43235 | 3/20 | 0.60 |
| ▸ | GLP1R | P43220 | 8/20 | 0.59 |
| ▸ | GCGR | P47871 | 7/20 | 0.59 |
| ▸ | CTSH | P09668 | 1/20 | 0.59 |
| ▸ | MC4R | P32245 | 2/20 | 0.57 |
| ▸ | MC5R | P33032 | 2/20 | 0.57 |
| ▸ | MC3R | P41968 | 2/20 | 0.57 |
| ▸ | MC1R | Q01726 | 2/20 | 0.57 |
| ▸ | GIPR | P48546 | 4/20 | 0.57 |
| ▸ | CALCA | P06881 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822027 | 1.00 | C5AR1 (0.76) | C5AR1IL23RCXCR4CTSLCTSS | |
| SCHEMBL30301165 | 0.89 | C5AR1 (0.67) | C5AR1IL23RCXCR4CTSLCTSS | |
| SCHEMBL29662252 | 0.89 | C5AR1 (0.66) | C5AR1CXCR4MC4R | |
| SCHEMBL30800876 | 0.88 | C5AR1 (0.72) | C5AR1IL23RCXCR4CTSLCTSS | |
| SCHEMBL30427315 | 0.88 | C5AR1 (0.72) | C5AR1IL23RCXCR4CTSLCTSS | |
| SCHEMBL29697153 | 0.88 | C5AR1 (0.65) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL30577312 | 0.88 | C5AR1 (0.63) | C5AR1IL23RCXCR4CTSLCTSS | |
| SCHEMBL29660777 | 0.88 | C5AR1 (0.79) | C5AR1IL23RCXCR4CTSLCTSS | |
| SCHEMBL29660814 | 0.88 | C5AR1 (0.79) | C5AR1IL23RCXCR4CTSLCTSS | |
| SCHEMBL16455231 | 0.88 | C5AR1 (0.68) | C5AR1IL23RCXCR4CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994554-A | Treatment of immune disorders, tumor inhibition | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1991-02-19 | — | — | US | disclosed |
| WO-1989010735-A1 | PROBURSIN | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1989-11-16 | — | — | WO | disclosed |
| EP-0342015-A2 | Peptides, their use and pharmaceutical compositions containing them | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1989-11-15 | — | — | EP | disclosed |