Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822317 | 0.87 | KDM4E (0.51) | KDM4ERECQLALDH1A1TP53ALOX15 | |
| SCHEMBL9822154 | 0.87 | KDM4E (0.39) | KDM4ERECQLALDH1A1TP53KMT2A | |
| SCHEMBL9821955 | 0.87 | TP53 (0.42) | KDM4EALDH1A1TP53HTTL3MBTL1 | |
| SCHEMBL9821957 | 0.84 | KDM4E (0.37) | KDM4ERECQLALDH1A1L3MBTL1KMT2A | |
| SCHEMBL10396813 | 0.83 | KDM4E (0.36) | KDM4EALDH1A1TP53KMT2AMAPT | |
| SCHEMBL9822141 | 0.78 | KDM4E (0.50) | KDM4ERECQLALDH1A1TP53ALOX15 | |
| SCHEMBL27387597 | 0.76 | KDM4E (0.37) | KDM4ERECQLALDH1A1TP53ALOX15 | |
| SCHEMBL9142508 | 0.75 | KDM4E (0.36) | KDM4EALDH1A1TP53KMT2APOLB | |
| SCHEMBL9822263 | 0.74 | TP53 (0.39) | KDM4EALDH1A1TP53HTTL3MBTL1 | |
| SCHEMBL19195006 | 0.74 | KDM4E (0.36) | KDM4ERECQLALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |