Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822154 | 0.87 | KDM4E (0.39) | TP53ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL9821955 | 0.87 | TP53 (0.42) | TP53L3MBTL1ALDH1A1POLBHPGD | |
| SCHEMBL27387599 | 0.85 | KDM4E (0.33) | TP53ALDH1A1POLBLMNAKDM4E | |
| SCHEMBL10396813 | 0.83 | KDM4E (0.36) | TP53ALDH1A1POLBKDM4EMAPT | |
| SCHEMBL9142908 | 0.83 | DPP4 (0.43) | L3MBTL1ALDH1A1POLBHPGDKDM4E | |
| SCHEMBL9822141 | 0.78 | KDM4E (0.50) | TP53ALDH1A1POLBKDM4EHTT | |
| SCHEMBL27385291 | 0.77 | POLB (0.38) | TP53L3MBTL1ALDH1A1POLBHPGD | |
| SCHEMBL9822108 | 0.74 | KDM4E (0.40) | TP53L3MBTL1ALDH1A1POLBKDM4E | |
| SCHEMBL27387597 | 0.73 | KDM4E (0.37) | TP53ALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL9142508 | 0.72 | KDM4E (0.36) | TP53ALDH1A1POLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |