Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822087 | 0.87 | RECQL (0.58) | RECQLALDH1A1HTTKDM4ETSHR | |
| SCHEMBL1464710 | 0.84 | RECQL (0.73) | RECQLALDH1A1HTTKDM4ETSHR | |
| SCHEMBL9822139 | 0.81 | RECQL (0.35) | RECQLALDH1A1HTTKDM4E | |
| SCHEMBL7100505 | 0.81 | RECQL (0.54) | RECQLALDH1A1HTTKDM4ETSHR | |
| SCHEMBL9822209 | 0.81 | RECQL (0.50) | RECQLALDH1A1HTTKDM4ETSHR | |
| SCHEMBL9300412 | 0.80 | RECQL (0.53) | RECQLALDH1A1HTTKDM4ETSHR | |
| SCHEMBL18373030 | 0.80 | RECQL (0.53) | RECQLALDH1A1HTTKDM4ETSHR | |
| SCHEMBL9822117 | 0.78 | RECQL (0.33) | RECQLALDH1A1HTT | |
| SCHEMBL9822393 | 0.76 | ALDH1A1 (0.34) | RECQLALDH1A1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL9822191 | 0.76 | TSHR (0.34) | RECQLALDH1A1HTTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |