Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164233 | 0.84 | SRD5A2 (0.65) | SRD5A2LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8164230 | 0.84 | SRD5A2 (0.65) | SRD5A2LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9822820 | 0.81 | SRD5A2 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL8255886 | 0.78 | MAPK1 (0.65) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2981380 | 0.76 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2980777 | 0.76 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2981376 | 0.76 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22449551 | 0.76 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL19733059 | 0.76 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL643029 | 0.76 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289327-B1 | STEROID 5-ALPHA-REDUCTASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-18 | — | — | EP | claimed |