Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 2/20 | 0.58 |
| ▸ | MMP8 | P22894 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ECE1 | P42892 | 7/20 | 0.57 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29493334 | 1.00 | ACE (0.61) | ACEKDM4EPOLBAPAF1MAPT | |
| SCHEMBL31571452 | 0.94 | MMP2 (0.58) | ACEKDM4EPOLBAPAF1MAPT | |
| SCHEMBL3855087 | 0.90 | ACE (0.56) | ACEKDM4EPOLBAPAF1MAPT | |
| SCHEMBL3855086 | 0.90 | ACE (0.56) | ACEKDM4EPOLBAPAF1MAPT | |
| SCHEMBL30051742 | 0.90 | ACE (0.68) | ACEECE1P2RY14ALOX15 | |
| SCHEMBL30051401 | 0.89 | ACE (0.59) | ACEKDM4EPOLBAPAF1MAPT | |
| SCHEMBL9822645 | 0.89 | ECE1 (0.68) | ACEMMP9MMP8ECE1MMP1 | |
| SCHEMBL30051404 | 0.89 | ECE1 (0.68) | ACEMMP9MMP8ECE1MMP1 | |
| SCHEMBL30834730 | 0.89 | ACE (0.58) | ACEKDM4EPOLBAPAF1MAPT | |
| SCHEMBL9822708 | 0.88 | ACE (0.65) | ACEKDM4EPOLBAPAF1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234186-B1 | USE OF OLIGOPEPTIDS FOR THE TREATMENT OF CEREBRAL DISORDERS | Fresenius AG (DE) | 1991-11-06 | — | — | EP | disclosed |
| US-5036052-A | Containing a dipeptide of tryptophan and alanine or lecine and no stabilizer; discoloration inhibition | MORISHITA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-30 | — | — | US | disclosed |
| EP-0347890-A1 | Amino acid nutrient compositions | Roussel Morishita Co., Ltd. (JP) | 1989-12-27 | — | — | EP | disclosed |
| EP-0234186-A1 | Use of oligopeptids for the treatment of cerebral disorders | Fresenius AG (DE) | 1987-09-02 | — | — | EP | disclosed |