Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | THPO | P40225 | 2/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 7/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766585 | 0.88 | CACNA1F (0.51) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9787339 | 0.85 | CACNA1F (0.62) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9787471 | 0.84 | HIF1A (0.57) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9787403 | 0.84 | CACNA1F (0.68) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9787465 | 0.83 | HIF1A (0.62) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9787472 | 0.79 | CACNA1F (0.57) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9787287 | 0.79 | MEN1 (0.61) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10663251 | 0.79 | CACNA1B (0.49) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10663093 | 0.79 | CACNA1B (0.49) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10756245 | 0.79 | CACNA1C (0.60) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172029-B1 | 1,4-DIHYDROPYRIDINES | JOHN WYETH & BROTHER LIMITED (GB) | 1991-02-27 | — | — | EP | claimed |
| CN-85106495-A | The method for preparing heterogeneous ring compound | — | 1987-02-11 | — | — | CN | claimed |
| EP-0172029-A1 | 1,4-Dihydropyridines | JOHN WYETH & BROTHER LIMITED (GB) | 1986-02-19 | — | — | EP | claimed |