Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823064 | 0.82 | TLR9 (0.49) | TNKSLMNAALDH1A1GAANPC1 | |
| SCHEMBL9823335 | 0.81 | LMNA (0.55) | TNKSLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL9822718 | 0.79 | TNKS (0.48) | TNKSLMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9823035 | 0.78 | LMNA (0.51) | TNKSLMNAKDM4ENPC1RAB9A | |
| SCHEMBL9822749 | 0.78 | LMNA (0.55) | TNKSLMNAKMT2AMEN1PTGER3 | |
| SCHEMBL542225 | 0.78 | TNKS (0.62) | TNKSLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL542484 | 0.75 | LMNA (0.70) | TNKSLMNAALDH1A1HPGDKMT2A | |
| SCHEMBL79379 | 0.74 | LMNA (0.57) | TNKSLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL29408442 | 0.74 | LMNA (0.57) | TNKSLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL30059113 | 0.74 | LMNA (0.57) | TNKSLMNAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288898-B1 | SUBSTITUTED CHINOXALYL-IMIDAZOLIDINE-2,4-DIONES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND PHARMACOLOGICAL PREPARATIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4943576-A | ENZYME INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-24 | — | — | US | disclosed |