⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660956 | 0.90 | — | — | |
| SCHEMBL9823024 | 0.87 | — | — | |
| SCHEMBL13532584 | 0.85 | — | — | |
| SCHEMBL13532586 | 0.84 | HTR1A (0.50) | — | |
| SCHEMBL9527435 | 0.84 | — | — | |
| SCHEMBL10556971 | 0.84 | HTR1A (0.55) | — | |
| SCHEMBL9526336 | 0.83 | — | — | |
| SCHEMBL9823084 | 0.83 | — | — | |
| SCHEMBL9600927 | 0.82 | HTR1A (0.44) | — | |
| SCHEMBL9527982 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286263-B1 | PSYCHOTROPIC POLYCYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-15 | — | — | EP | claimed |
| US-4797488-A | N-((4-(PHENYL OR HETEROCYCLIC)PIPERAZIN-1-YL)ALKYL)-1,5-METHANOCYCLOPENT(D)AZEPINE-2,4 -DIONES; ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-10 | — | — | US | claimed |
| EP-0286263-A1 | Psychotropic polycyclic imides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-10-12 | — | — | EP | claimed |
| EP-0286263-B1 | PSYCHOTROPIC POLYCYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-15 | — | — | EP | disclosed |
| US-4824999-A | INTERMEDIATES FOR ANTIPSYCHOTIC AND ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |
| US-4797488-A | N-((4-(PHENYL OR HETEROCYCLIC)PIPERAZIN-1-YL)ALKYL)-1,5-METHANOCYCLOPENT(D)AZEPINE-2,4 -DIONES; ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-10 | — | — | US | disclosed |