Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 12/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823169 | 0.89 | GRM2 (0.61) | CYP2C9GRM2CYP1A2CYP2C19 | |
| SCHEMBL28849018 | 0.89 | GRM2 (0.61) | CYP2C9GRM2CYP1A2CYP2C19 | |
| SCHEMBL29950085 | 0.89 | GRM2 (0.61) | CYP2C9GRM2CYP1A2CYP2C19 | |
| SCHEMBL29950193 | 0.89 | GRM2 (0.61) | CYP2C9GRM2CYP1A2CYP2C19 | |
| SCHEMBL4093180 | 0.84 | GRM2 (0.46) | ALDH1A1CYP2C9CYP3A4CYP2D6GRM2 | |
| SCHEMBL4761279 | 0.84 | GRM2 (0.46) | ALDH1A1CYP2C9CYP3A4CYP2D6GRM2 | |
| SCHEMBL4277020 | 0.84 | GRM2 (0.57) | CYP2C9GRM2CYP1A2CYP2C19ADRA1D | |
| SCHEMBL4574440 | 0.83 | CALML3 (0.47) | ALDH1A1CYP2C9CYP3A4CYP2D6GRM2 | |
| SCHEMBL16701320 | 0.81 | CALML3 (0.49) | CYP2C9CYP3A4CYP2D6GRM2CYP1A2 | |
| SCHEMBL16701317 | 0.81 | CALML3 (0.49) | CYP2C9CYP3A4CYP2D6GRM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184170-B1 | AMINOMETHYL OXOOXAZOLIDINYL BENZENE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |