Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 18/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849018 | 1.00 | GRM2 (0.61) | GRM2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9823169 | 1.00 | GRM2 (0.61) | GRM2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29950193 | 1.00 | GRM2 (0.61) | GRM2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9823246 | 0.89 | ALDH1A1 (0.53) | GRM2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3166083 | 0.86 | GRM2 (0.58) | GRM2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3166079 | 0.86 | GRM2 (0.58) | GRM2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4761279 | 0.86 | GRM2 (0.46) | GRM2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13528058 | 0.86 | GRM2 (0.58) | GRM2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4277020 | 0.86 | GRM2 (0.57) | GRM2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4093180 | 0.86 | GRM2 (0.46) | GRM2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |