Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629293 | 0.78 | KCNH2 (0.47) | KCNH2CNR2CNR1CYP19A1KDM5A | |
| SCHEMBL28221869 | 0.77 | KCNH2 (0.50) | KCNH2CNR2CNR1CYP19A1KDM5A | |
| SCHEMBL27710988 | 0.77 | KCNH2 (0.46) | KCNH2CNR2CNR1CYP19A1KDM5A | |
| SCHEMBL19578802 | 0.77 | KCNH2 (0.50) | KCNH2CNR2CNR1CYP19A1KDM5A | |
| SCHEMBL8664135 | 0.76 | KCNH2 (0.48) | KCNH2CNR2CNR1CYP19A1KDM5A | |
| SCHEMBL27711036 | 0.76 | KCNH2 (0.44) | KCNH2CNR2CNR1CYP19A1KDM5A | |
| Bromide SCHEMBL28491346 | 0.76 | KCNH2 (0.48) | KCNH2CNR2CNR1CYP19A1KDM5A | |
| SCHEMBL26048236 | 0.76 | KCNH2 (0.44) | KCNH2CNR2CNR1CYP19A1KDM5A | |
| SCHEMBL370840 | 0.76 | KCNH2 (0.44) | KCNH2CNR2CNR1CYP19A1KDM5A | |
| SCHEMBL29139297 | 0.74 | KCNH2 (0.43) | KCNH2CNR2CNR1CYP19A1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245646-B1 | PROCESS FOR THE PREPARATION OF 1-ARYL-5-AMINO-PYRAZOLES | BAYER AG (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0245646-A1 | Process for the preparation of 1-aryl-5-amino-pyrazoles | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |