SCHEMBL982334

SCHEMBL982334

C#Cc1cccc(C#C)n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37
HDAC8 Q9BY41 2/20 0.33
MAP3K14 Q99558 1/20 0.33
GRM5 P41594 5/20 0.32
PDE2A O00408 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169469 0.87 SOS2 (0.42) CYP1A1CYP1B1
SCHEMBL22846483 0.83 GRM5 (0.37) MAP3K14GRM5NPC1RAB9ASMN1; SMN2
SCHEMBL30713894 0.82
SCHEMBL3470535 0.82
SCHEMBL3510212 0.82
SCHEMBL31646381 0.82
SCHEMBL2714827 0.82
SCHEMBL18737312 0.82
SCHEMBL16288839 0.82
SCHEMBL2230973 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217625-B CNC (computer numerical control) tridentate ruthenium complex as well as preparation method and application thereof 南方科技大学 2024-08-06 CN claimed
CN-115960142-B Metal heterocyclic compound containing ring osmium vinylidene bond, and synthetic method and application thereof 南方科技大学 2024-01-26 CN claimed
CN-115960142-A Metal heterocyclic compound containing intra-ring osmium ethylene bond and synthesis method and application thereof 南方科技大学 2023-04-14 CN claimed
CN-115947721-A Palladium extracting agent and preparation method and application thereof 四川大学 2023-04-11 CN claimed
CN-115124715-A Preparation method of pyridyl polythioamide 华南理工大学 2022-09-30 CN claimed
CN-114653344-A Triazole gel material, preparation method thereof and application of triazole gel material in adsorption of organic pollutants 中山大学 2022-06-24 CN claimed
CN-108279224-B A method of persulfuric acid ion concentration is detected with conjugated polyelectrolytes-silver HUNAN NORMAL UNIVERSITY (CN) 2019-10-29 CN claimed
CN-102660000-B Conjugated polyelectrolyte with ratiometric fluorescence signals, preparation method and application thereof UNIV HUNAN NORMAL 2014-09-24 CN claimed
CN-103788370-A Method for preparing polymer nanospheres and nanorods by virtue of ultrasonic-assisted soap-free click polymerization reaction UNIV NORTHWEST A&F 2014-05-14 CN claimed
JP-58021420-A None JP disclosed
CN-122060170-A Polyacetylene selenoether compound and preparation method and application thereof 华南理工大学 2026-05-19 CN disclosed
WO-2025137293-A2 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS Roche Sequencing Solutions, Inc. (US) 2025-06-26 WO disclosed
US-20250075265-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS ROCHE SEQUENCING SOLUTIONS INC (US) 2025-03-06 US disclosed
CN-116217625-B CNC (computer numerical control) tridentate ruthenium complex as well as preparation method and application thereof 南方科技大学 2024-08-06 CN disclosed
US-20020064953-A1 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORPORATION (JP) 2002-05-30 US disclosed
EP-1188807-A2 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR Corporation (JP) 2002-03-20 EP disclosed
EP-1099719-A1 Diyne-containing (co) polymer, processes for producing the same, and cured film JSR Corporation (JP) 2001-05-16 EP disclosed
WO-1993002983-A1 SOLUTION OF A SOLUBILIZABLE VITREOUS CARBON PRECURSOR, VITREOUS CARBON COATING MADE FROM SUCH A SOLUTION FOR APPLICATION AT LOW TEMPERATURE, AND OBJECTS, ESPECIALLY OPTICAL FIBRES, HAVING SUCH COATING FORT FIBRES OPTIQUES RECHERCHE ET TECHNOLOGIE (FR) 1993-02-18 WO disclosed
JP-S5821420-A CONJUGATED ALTERNATING COPOLYMER JAPAN SYNTHETIC RUBBER CO LTD 1983-02-08 JP disclosed
EP-0059646-A2 Conjugated polymers and processes for preparing and modifying them JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250075265-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS POLN, POLB, POLRMT CYP1A1 409/4885CYP1B1 922/4885HDAC8 3092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.