Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.40 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823480 | 1.00 | HDAC1 (0.52) | HDAC1HDAC2HCAR2KDM4EALDH1A1 | |
| SCHEMBL18237505 | 0.87 | HDAC1 (0.54) | HDAC1HDAC2HCAR2KDM4EALDH1A1 | |
| SCHEMBL18237506 | 0.87 | HDAC1 (0.54) | HDAC1HDAC2HCAR2KDM4EALDH1A1 | |
| SCHEMBL11001535 | 0.85 | HDAC1 (0.52) | HDAC1HDAC2HCAR2KDM4EALDH1A1 | |
| SCHEMBL11001540 | 0.85 | HDAC1 (0.52) | HDAC1HDAC2HCAR2KDM4EALDH1A1 | |
| SCHEMBL9823341 | 0.81 | HDAC1 (0.52) | HDAC1HDAC2HCAR2KDM4EALDH1A1 | |
| SCHEMBL10717845 | 0.78 | HCAR2 (0.42) | HDAC1HDAC2HCAR2KDM4EALDH1A1 | |
| SCHEMBL10717859 | 0.78 | HCAR2 (0.42) | HDAC1HDAC2HCAR2KDM4EALDH1A1 | |
| SCHEMBL5704559 | 0.74 | — | — | |
| SCHEMBL5704550 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208040-B1 | RHODANINE DERIVATIVES AND A PROCESS FOR PREPARING SAME | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4777259-A | ALDOSE REDUCTASE INHIBITOR | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-10-11 | — | — | US | disclosed |
| EP-0258914-A2 | Rhodanine derivatives and a process for preparing same | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1988-03-09 | — | — | EP | disclosed |
| US-4714765-A | Rhodanine derivatives and process for preparing the same | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1987-12-22 | — | — | US | disclosed |
| EP-0208040-A2 | Rhodanine derivatives and a process for preparing same | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1987-01-14 | — | — | EP | disclosed |