Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658967 | 0.81 | — | — | |
| SCHEMBL28654671 | 0.80 | ALDH1A1 (0.33) | TP53TSHR | |
| SCHEMBL3812223 | 0.79 | — | — | |
| SCHEMBL5183618 | 0.79 | — | — | |
| SCHEMBL23482770 | 0.77 | — | — | |
| SCHEMBL7706976 | 0.77 | TP53 (0.35) | TP53TSHRSLC7A5 | |
| SCHEMBL19028042 | 0.76 | TP53 (0.38) | TP53TSHRSLC7A5 | |
| SCHEMBL9620468 | 0.73 | TP53 (0.32) | TP53 | |
| SCHEMBL14636311 | 0.73 | SLC1A3 (0.32) | TP53 | |
| SCHEMBL21436746 | 0.72 | RNPEP (0.41) | RNPEPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265305-B1 | 5-PYRAZOLONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS HERBICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1991-06-12 | — | — | EP | disclosed |
| EP-0265305-A1 | 5-Pyrazolone derivatives, process for their preparation, their use as herbicides and compositions containing them | ROUSSEL-UCLAF (FR) | 1988-04-27 | — | — | EP | disclosed |