Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10769481 | 0.74 | KMT2A (0.52) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL9390510 | 0.72 | MEN1 (0.63) | MEN1KMT2ATDP1CYP19A1POLB | |
| SCHEMBL10768910 | 0.71 | KMT2A (0.47) | MEN1KMT2ATDP1CYP19A1POLB | |
| SCHEMBL9270006 | 0.70 | KMT2A (0.49) | MEN1KMT2ATDP1CYP19A1POLB | |
| SCHEMBL10333856 | 0.70 | MEN1 (0.45) | MEN1KMT2ATDP1EGFRPOLB | |
| SCHEMBL9272801 | 0.69 | MEN1 (0.47) | MEN1KMT2ATDP1CYP19A1POLB | |
| SCHEMBL9823627 | 0.69 | MEN1 (0.68) | MEN1KMT2ATDP1CYP19A1POLB | |
| SCHEMBL10767967 | 0.68 | MEN1 (0.49) | MEN1KMT2ATDP1CYP19A1POLB | |
| SCHEMBL10767970 | 0.68 | MEN1 (0.49) | MEN1KMT2ATDP1CYP19A1POLB | |
| SCHEMBL10734466 | 0.66 | KMT2A (0.78) | MEN1KMT2ATDP1CYP19A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301393-B1 | 1,4-DISUBSTITUTED 1-AZOLYL-3,3-DYMETHYLBUTANE DERIVATIVES | BAYER AG (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4968712-A | PHYTOPATHOGENS, AGRICULTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0301393-A1 | 1,4-Disubstituted 1-azolyl-3,3-dymethylbutane derivatives | BAYER AG (DE) | 1989-02-01 | — | — | EP | disclosed |