Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 18/20 | 0.65 |
| ▸ | TTR | P02766 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394900 | 0.79 | NOTUM (1.00) | NOTUM | |
| SCHEMBL29664563 | 0.79 | NOTUM (1.00) | NOTUM | |
| SCHEMBL27784446 | 0.79 | TTR (1.00) | TTRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL3943150 | 0.79 | NOTUM (0.65) | NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL13723672 | 0.79 | NOTUM (1.00) | NOTUMKDM4EALDH1A1 | |
| SCHEMBL18394585 | 0.76 | NOTUM (0.61) | NOTUMKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29664885 | 0.76 | NOTUM (0.61) | NOTUMKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29664535 | 0.75 | ALDH1A1 (0.68) | NOTUMKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL18394492 | 0.75 | ALDH1A1 (0.68) | NOTUMKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3940570 | 0.73 | NOTUM (0.58) | NOTUMKDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209230-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4764205-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| US-4699647-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0209230-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-21 | — | — | EP | disclosed |