Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823535 | 0.83 | NPC1 (0.57) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9823841 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRLMNASMN1; SMN2MAPK1 | |
| SCHEMBL9823457 | 0.80 | PDE7A (0.46) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9823531 | 0.79 | PDE7A (0.57) | ALDH1A1MAPK1NPC1RAB9AKDM4E | |
| SCHEMBL9823781 | 0.78 | NPC1 (0.45) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6483730 | 0.78 | PDE7A (0.58) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9823310 | 0.76 | SMN1; SMN2 (0.52) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9823879 | 0.76 | PDE7A (0.59) | ALDH1A1TSHRSMN1; SMN2MAPK1NPC1 | |
| SCHEMBL9823827 | 0.75 | PDE7A (0.44) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9671587 | 0.74 | PDE7A (0.69) | ALDH1A1TSHRLMNASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276826-B1 | 2-ALKYLSULFINYL-4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4833144-A | ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0276826-A1 | 2-Alkylsulfinyl-4 (3H)-quinazolinone derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |