Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823827 | 0.71 | PDE7A (0.44) | ALDH1A1KDM4EPDE7AHTR6NPC1 | |
| SCHEMBL9823535 | 0.71 | NPC1 (0.57) | ALDH1A1KDM4EPDE7ANPC1RAB9A | |
| SCHEMBL9671584 | 0.71 | ALDH1A1 (0.61) | ALDH1A1PDE7AHTR6TSHRLMNA | |
| SCHEMBL31540623 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KDM4EPDE7AHTR6NPC1 | |
| SCHEMBL9823531 | 0.68 | PDE7A (0.57) | ALDH1A1KDM4EPDE7ANPC1RAB9A | |
| SCHEMBL30122631 | 0.67 | MAPK1 (0.75) | ALDH1A1KDM4ELMNAL3MBTL1POLB | |
| SCHEMBL1682746 | 0.67 | MAPK1 (0.75) | ALDH1A1KDM4ELMNAL3MBTL1POLB | |
| SCHEMBL9823841 | 0.67 | ALDH1A1 (0.55) | ALDH1A1KDM4EPDE7ANPC1RAB9A | |
| SCHEMBL6483730 | 0.67 | PDE7A (0.58) | ALDH1A1KDM4EPDE7ANPC1RAB9A | |
| SCHEMBL9823457 | 0.67 | PDE7A (0.46) | ALDH1A1KDM4EPDE7ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276826-B1 | 2-ALKYLSULFINYL-4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4833144-A | ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0276826-A1 | 2-Alkylsulfinyl-4 (3H)-quinazolinone derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |