Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728563 | 1.00 | CYP1A2 (0.50) | CYP1A2KDM4EAHRPTGS1FBP1 | |
| SCHEMBL10846493 | 0.79 | KDM4E (0.64) | KDM4EAHRFBP1CA1CA2 | |
| SCHEMBL3144474 | 0.79 | KDM4E (0.64) | KDM4EAHRFBP1CA1CA2 | |
| SCHEMBL22931544 | 0.79 | AHR (0.68) | CYP1A2AHRPTGS1FBP1NQO2 | |
| SCHEMBL13790273 | 0.79 | AHR (0.68) | CYP1A2AHRPTGS1FBP1NQO2 | |
| SCHEMBL13790263 | 0.79 | AHR (0.68) | CYP1A2AHRPTGS1FBP1NQO2 | |
| SCHEMBL23373872 | 0.79 | KDM4E (0.55) | CYP1A2KDM4EKIF11 | |
| SCHEMBL1224350 | 0.79 | CYP1A2 (0.55) | CYP1A2AHRPTGS1FBP1NQO2 | |
| SCHEMBL22029549 | 0.79 | KDM4E (0.55) | CYP1A2KDM4EKIF11 | |
| SCHEMBL3594422 | 0.79 | RPS6KA3 (0.45) | KDM4EAHRPTGS1FBP1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003669-A | Preparation method of unsaturated nitrile, N-15 marked unsaturated nitrile and N-15 marked rilpivirine | 北京化工大学 | 2023-11-07 | — | — | CN | disclosed |
| EP-2822933-B1 | CUCN-MEDIATED ONE POT PRODUCTION OF CINNAMONITRILE DERIVATIVES | COUNCIL SCIENT IND RES (IN) | 2016-12-28 | — | — | EP | disclosed |
| US-9096498-B2 | CuCN-mediated one pot production of cinnamonitrile derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-08-04 | — | — | US | disclosed |
| US-20150031899-A1 | CUCN-MEDIATED ONE POT PRODUCTION OF CINNAMONITRILE DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-29 | — | — | US | disclosed |
| EP-2822933-A1 | CUCN-MEDIATED ONE POT PRODUCTION OF CINNAMONITRILE DERIVATIVES | Council of Scientific & Industrial Research (IN) | 2015-01-14 | — | — | EP | disclosed |
| WO-2013132520-A1 | CUCN-MEDIATED ONE POT PRODUCTION OF CINNAMONITRILE DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-09-12 | — | — | WO | disclosed |
| US-7332622-B2 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2008-02-19 | — | — | US | disclosed |
| US-7332622-B2 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2008-02-19 | — | — | US | disclosed |
| EP-0174769-B1 | ANTIFUNGAL AZOLE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-21 | — | — | EP | disclosed |
| US-4925863-A | 1,3-DI(1,2,4-TRIAZOL-1-YL)-2-PROPANOL DERIVATIVES SUBSTITUTED WITH A STYRYL GROUP | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| US-4785007-A | ANTIDEPRESSANTS, P | LABORATOIRES HOECHST S.A. (FR) | 1988-11-15 | — | — | US | disclosed |
| US-4533655-A | Analgesic dipeptide amides and method of use and compositions thereof | STERLING DRUG INC. (US) | 1985-08-06 | — | — | US | disclosed |
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4322429-A | Isoxazolylbenzamides as insecticides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0048162-A1 | Isoxazolylbenzamides | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0042732-A1 | 1-benzoyl-3-substituted ureas and thioureas, their preparation, insecticidal formulations containing them and their use as insecticides | ELI LILLY AND COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4012377-A | ANTIMICROBIAL, PARASITICIDES | GLAXO LABORATORIES LIMITED (EN) | 1977-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031899-A1 | CUCN-MEDIATED ONE POT PRODUCTION OF CINNAMONITRILE DERIVATIVES | NISCH, PNN, NCLN | CYP1A2 1517/4885KDM4E 3599/4885AHR 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.