⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL1361847 | 1.00 | — | — | |
| Ether SCHEMBL9750539 | 1.00 | ALDH1A1 (0.41) | — | |
| Ether SCHEMBL310584 | 0.95 | — | — | |
| Ether SCHEMBL811889 | 0.95 | ALDH1A1 (0.44) | — | |
| Ether SCHEMBL1345656 | 0.95 | — | — | |
| Ether SCHEMBL699018 | 0.95 | — | — | |
| Ether SCHEMBL11802524 | 0.90 | — | — | |
| Ether SCHEMBL421875 | 0.90 | — | — | |
| Ether SCHEMBL21326457 | 0.90 | — | — | |
| Ether SCHEMBL1133979 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062728-A | Synthetic method of 3, 5-dichloro-6-ethylpyrazine formamide | 上海鑫凯化学科技有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-111760021-A | Conjugate containing alpha-galactosylceramide analogue and saccharide antigen as well as preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2020-10-13 | — | — | CN | claimed |
| US-12612424-B2 | HPK1 inhibitors and uses thereof | REGOR PHARMACEUTICALS, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-12281101-B2 | Bicyclic lactams and methods of use thereof | GENENTECH, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| EP-3760625-B1 | BICYCLIC LACTAMS AS RECEPTOR-INTERACTING PROTEIN-1 (RIP1) KINASE INHIBITORS FOR TREATING E.G. INFLAMMATORY DISEASES | HOFFMANN LA ROCHE (CH) | 2024-03-27 | — | — | EP | disclosed |
| US-11708344-B2 | Flavone derivatives for the treatment and prophylaxis of hepatitis B virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-11667824-B2 | Adhesive and its preparation and application | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2023-06-06 | — | — | US | disclosed |
| US-20230074887-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | HOFFMANN-LA ROCHE INC. (US) | 2023-03-09 | — | — | US | disclosed |
| CN-115703796-A | Preparation method of important intermediate of Reidesciclovir | 苏州恩泰新材料科技有限公司 | 2023-02-17 | — | — | CN | disclosed |
| US-20220389037-A1 | HPK1 INHIBITORS AND USES THEREOF | REGOR PHARMACEUTICALS, INC. | 2022-12-08 | — | — | US | disclosed |
| US-20220348559-A1 | BICYCLIC LACTAMS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2022-11-03 | — | — | US | disclosed |
| WO-2014023258-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F.HOFFMANN-LA ROCHE AG (CH) | 2014-02-13 | — | — | WO | disclosed |
| EP-0194846-B1 | PREPARATION OF THIENO-IMIDAZOLE DERIVATIVES | PFIZER INC. (US) | 1991-05-08 | — | — | EP | disclosed |
| US-4895679-A | Process for production of chenodeoxycholic acid and novel intermediates useful for the process | PRIME CHEMICALS TECHNOLOGY CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| US-4670564-A | Preparation of thieno-imidazole derivatives | PFIZER INC. (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0069810-B1 | NOVEL DIBENZOXEPINS, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THE USE OF DIBENZOXEPINS IN THE TREATMENT OF ALLERGIC CONDITIONS | MERCK & CO. INC. (US) | 1986-12-03 | — | — | EP | disclosed |
| EP-0194846-A2 | Preparation of thieno-imidazole derivatives | PFIZER INC. (US) | 1986-09-17 | — | — | EP | disclosed |
| EP-0069810-A1 | Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | disclosed |
| US-4282365-A | Dibenz[b,e]oxepin compounds | MERCK & CO., INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-3966755-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |