Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12923092 | 1.00 | BACE1 (0.62) | BACE1CYP1A2KDM4ELMNAPOLB | |
| SCHEMBL16189309 | 0.93 | BACE1 (0.56) | BACE1CYP1A2KDM4ELMNAPOLB | |
| SCHEMBL16189304 | 0.89 | BACE1 (0.51) | BACE1CYP1A2KDM4ELMNAPOLB | |
| SCHEMBL15037486 | 0.86 | CYP1A2 (0.70) | BACE1CYP1A2KDM4ELMNAPOLB | |
| SCHEMBL16974223 | 0.83 | CYP1A2 (0.55) | BACE1CYP1A2KDM4ELMNAPOLB | |
| SCHEMBL31307097 | 0.83 | CYP1A2 (0.55) | BACE1CYP1A2KDM4ELMNAPOLB | |
| SCHEMBL19009556 | 0.81 | BACE1 (0.43) | BACE1CYP1A2 | |
| SCHEMBL12436949 | 0.80 | CYP1A2 (0.52) | BACE1CYP1A2KDM4ELMNAPOLB | |
| SCHEMBL16189322 | 0.80 | — | — | |
| SCHEMBL23246579 | 0.80 | BACE1 (0.67) | BACE1CYP1A2KDM4EPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073423-A | Quinoline derivative and preparation method and application thereof | 广东工业大学 | 2022-09-20 | — | — | CN | claimed |
| CN-109111397-B | Quinoline aromatic ethylene derivative and preparation method and application thereof | 广东工业大学 | 2021-12-10 | — | — | CN | claimed |
| CN-109111396-B | Quinoline aromatic vinyl derivative and preparation method and application thereof | 广东工业大学 | 2021-09-03 | — | — | CN | claimed |
| CN-109776406-B | Method for cross coupling of ether compound and quinoline derivative | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-109111397-A | A kind of quinoline aromatic ethylene analog derivative and its preparation method and application | 广东工业大学 | 2019-01-01 | — | — | CN | claimed |
| CN-109111396-A | A kind of quinoline aromatic ethylene analog derivative and its preparation method and application | 广东工业大学 | 2019-01-01 | — | — | CN | claimed |
| CN-115073423-B | Quinoline derivative and preparation method and application thereof | 广东工业大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-115073423-A | Quinoline derivative and preparation method and application thereof | 广东工业大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-109111397-B | Quinoline aromatic ethylene derivative and preparation method and application thereof | 广东工业大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-109111396-B | Quinoline aromatic vinyl derivative and preparation method and application thereof | 广东工业大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-106543078-B | A kind of preparation method of quinoline | 中国科学院兰州化学物理研究所苏州研究院 | 2019-01-11 | — | — | CN | disclosed |
| CN-109111396-A | A kind of quinoline aromatic ethylene analog derivative and its preparation method and application | 广东工业大学 | 2019-01-01 | — | — | CN | disclosed |
| CN-109111397-A | A kind of quinoline aromatic ethylene analog derivative and its preparation method and application | 广东工业大学 | 2019-01-01 | — | — | CN | disclosed |
| US-20120241730-A1 | ORGANIC EL ELEMENT AND METHOD FOR MANUFACTURING ORGANIC EL ELEMENT | TORAY INDUSTRIES, INC. (JP) | 2012-09-27 | — | — | US | disclosed |
| US-20110006295-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | MERCK PATENT GMBH | 2011-01-13 | — | — | US | disclosed |
| US-20110006295-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | MERCK PATENT GMBH | 2011-01-13 | — | — | US | disclosed |
| US-20110006295-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | MERCK PATENT GMBH | 2011-01-13 | — | — | US | disclosed |
| EP-2250151-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | Merck Patent GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009112854-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | MERCK PATENT GMBH (DE) | 2009-09-17 | — | — | WO | disclosed |
| WO-2009112854-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | MERCK PATENT GMBH (DE) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110006295-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | NR2E3, NR4A2, NR4A3 | BACE1 4432/4885CYP1A2 544/4885KDM4E 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.