Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823633 | 0.80 | EPHX1 (0.43) | PPARGPPARA | |
| SCHEMBL2600033 | 0.77 | IDO1 (0.57) | IDO1KDRPYCR1P2RX7LMNA | |
| SCHEMBL9200306 | 0.76 | GSK3B (0.50) | LMNAPPARA | |
| SCHEMBL9380085 | 0.76 | SLC6A4 (0.48) | LMNAMAPTPPARGPPARA | |
| SCHEMBL1720743 | 0.74 | IDO1 (0.58) | IDO1KDRPYCR1P2RX7LMNA | |
| SCHEMBL31731921 | 0.73 | IDO1 (0.61) | IDO1KDRPYCR1P2RX7ABCB11 | |
| SCHEMBL120051 | 0.73 | IDO1 (0.61) | IDO1KDRPYCR1P2RX7ABCB11 | |
| SCHEMBL1590516 | 0.71 | RXRA (0.55) | IDO1KDRP2RX7ABCB11FAAH | |
| SCHEMBL30302148 | 0.71 | RXRA (0.55) | IDO1KDRP2RX7ABCB11FAAH | |
| SCHEMBL11434970 | 0.71 | IDO1 (0.54) | IDO1KDRPYCR1P2RX7ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301393-B1 | 1,4-DISUBSTITUTED 1-AZOLYL-3,3-DYMETHYLBUTANE DERIVATIVES | BAYER AG (DE) | 1991-08-14 | — | — | EP | disclosed |
| EP-0301393-A1 | 1,4-Disubstituted 1-azolyl-3,3-dymethylbutane derivatives | BAYER AG (DE) | 1989-02-01 | — | — | EP | disclosed |