Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9824043 | 0.98 | TSHR (0.55) | TSHRNPSR1CYP19A1KDM4ELMNA | |
| SCHEMBL9824431 | 0.81 | TSHR (0.57) | TSHRNPSR1CYP19A1KDM4ELMNA | |
| SCHEMBL9824805 | 0.79 | TSHR (0.55) | TSHRNPSR1CYP19A1KDM4ELMNA | |
| SCHEMBL1566072 | 0.78 | TSHR (0.69) | TSHRNPSR1CYP19A1KDM4ELMNA | |
| SCHEMBL9011515 | 0.78 | TSHR (0.69) | TSHRNPSR1CYP19A1KDM4ELMNA | |
| SCHEMBL9823939 | 0.73 | TSHR (0.57) | TSHRNPSR1CYP19A1KDM4ELMNA | |
| Ethosuximide SCHEMBL20980115 | 0.73 | TSHR (1.00) | TSHRNPSR1CYP19A1KDM4ELMNA | |
| Ethosuximide SCHEMBL4654769 | 0.73 | TSHR (1.00) | TSHRNPSR1CYP19A1KDM4ELMNA | |
| Ethosuximide SCHEMBL34212 | 0.73 | TSHR (1.00) | TSHRNPSR1CYP19A1KDM4ELMNA | |
| Ethosuximide SCHEMBL118395 | 0.73 | TSHR (1.00) | TSHRNPSR1CYP19A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |