Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824483 | 1.00 | MAPT (0.48) | MAPTHTTCYP1A1CYP1A2CYP1B1 | |
| Oxalic Acid SCHEMBL9824967 | 0.95 | MAPT (0.51) | MAPTHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9824630 | 0.91 | SLC2A1 (0.49) | MAPTHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL10759050 | 0.91 | SLC2A1 (0.49) | MAPTHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9824503 | 0.91 | SLC2A1 (0.49) | MAPTHTTCYP1A1CYP1A2CYP1B1 | |
| Hydrochloric Acid SCHEMBL9824621 | 0.90 | SLC2A1 (0.48) | MAPTHTTCYP1A1CYP1A2CYP1B1 | |
| Hydrochloric Acid SCHEMBL9824367 | 0.90 | SLC2A1 (0.48) | MAPTHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9824584 | 0.86 | SIGMAR1 (0.52) | MAPTHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9824510 | 0.86 | SIGMAR1 (0.52) | MAPTHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9824139 | 0.82 | CYP1A2 (0.46) | MAPTCYP1A1CYP1A2CYP1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250254-B1 | CIS & TRANS STILBENES AND THEIR COMPOSITION FOR THE TREATMENT OF HYPERTENSION | McNeilab, Inc. (US) | 1991-06-19 | — | — | EP | claimed |
| EP-0250254-A1 | Cis & trans stilbenes and their composition for the treatment of hypertension | McNeilab, Inc. (US) | 1987-12-23 | — | — | EP | claimed |
| EP-0250254-B1 | CIS & TRANS STILBENES AND THEIR COMPOSITION FOR THE TREATMENT OF HYPERTENSION | McNeilab, Inc. (US) | 1991-06-19 | — | — | EP | disclosed |