SCHEMBL9824554

SCHEMBL9824554

CCCOC(=O)c1cc(N(SC)C(=S)N2CCCCN2)c(F)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GUSB P08236 1/20 0.31
GAA P10253 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9824721 0.94 CYP1A2 (0.36) CYP1A2CYP2C19HPGDLMNAMAPT
SCHEMBL9824295 0.93 ALDH1A1 (0.34) CYP1A2CYP2C19HPGDLMNAMAPT
SCHEMBL9824165 0.88 HPGD (0.33) CYP1A2CYP2C19HPGDLMNAMAPT
SCHEMBL9824044 0.79 GSK3A (0.36) HPGDSMN1; SMN2
SCHEMBL9823983 0.76 CYP4F2 (0.39) LMNASMN1; SMN2
SCHEMBL9374250 0.74 KDM4E (0.33) CYP1A2HPGDSMN1; SMN2
SCHEMBL9764390 0.70 ALDH1A1 (0.44) CYP1A2CYP2C19HPGDLMNAMAPT
SCHEMBL9376872 0.70 ALDH1A1 (0.33) HPGDMAPT
SCHEMBL9248670 0.68 CYP1A2 (0.60) CYP1A2CYP2C19HPGDLMNAMAPT
SCHEMBL9824910 0.65 ALDH1A1 (0.47) LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273417-B1 THIADIAZABICYCLONONANE DERIVATIVES AND HERBICIDAL COMPOSITIONS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-08-21 EP disclosed
US-4906279-A Thiadiazabicyclononane derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO. (JP) 1990-03-06 US disclosed
EP-0273417-A1 Thiadiazabicyclononane derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-07-06 EP disclosed