Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635351 | 0.85 | GLA (0.46) | GLAMAP3K14CRBNHDAC8CYP19A1 | |
| SCHEMBL28479332 | 0.77 | MAP3K14 (0.50) | GLAMAP3K14CRBNHDAC8CYP19A1 | |
| SCHEMBL886958 | 0.75 | GLA (0.47) | GLAMAP3K14CRBNCYP19A1NPC1 | |
| SCHEMBL1056468 | 0.74 | MAP3K14 (0.43) | GLAMAP3K14CRBNHDAC8CYP19A1 | |
| SCHEMBL1838214 | 0.74 | MAP3K14 (0.43) | GLAMAP3K14CRBNHDAC8CYP19A1 | |
| SCHEMBL29129779 | 0.73 | MAP3K14 (0.46) | GLAMAP3K14CRBNHDAC8CYP19A1 | |
| SCHEMBL28450446 | 0.72 | GLA (0.45) | GLAMAP3K14CRBNHTTNPC1 | |
| SCHEMBL13378339 | 0.71 | — | — | |
| SCHEMBL18909611 | 0.71 | — | — | |
| SCHEMBL11274777 | 0.71 | MAP3K14 (0.44) | GLAMAP3K14CRBNHDAC8CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |