SCHEMBL886958

SCHEMBL886958

CC(C)CC1CC(=O)NC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.47
MAP3K14 Q99558 1/20 0.40
CRBN Q96SW2 4/20 0.38
MME P08473 1/20 0.36
NPC1 O15118 2/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
CCNA1 P78396 1/20 0.33
DDB1 Q16531 1/20 0.33
FFAR1 O14842 1/20 0.32
CYP19A1 P11511 1/20 0.32
CTSD P07339 1/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28450446 0.84 GLA (0.45) GLAMAP3K14CRBNNPC1DDB1
SCHEMBL3635351 0.82 GLA (0.46) GLAMAP3K14CRBNNPC1DDB1
SCHEMBL24440196 0.80 CRBN (0.49) CRBNDDB1
SCHEMBL28479332 0.77 MAP3K14 (0.50) GLAMAP3K14CRBNNPC1DDB1
SCHEMBL23758037 0.76 GLA (0.39) GLAMAP3K14CRBNDDB1FFAR1
SCHEMBL18909611 0.76
SCHEMBL1818235 0.76
SCHEMBL17907172 0.75 MAP3K14 (0.48) GLAMAP3K14CRBNNPC1DDB1
SCHEMBL31628300 0.75 CRBN (0.39) GLAMAP3K14CRBNMMENPC1
SCHEMBL9825087 0.75 GLA (0.44) GLAMAP3K14CRBNNPC1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117813365-A Friction modifier having improved friction characteristics and lubricating composition containing the same 路博润公司 2024-04-02 CN claimed
CN-116376622-A Coal-based engine oil and application thereof 国家能源集团宁夏煤业有限责任公司 2023-07-04 CN claimed
US-10604719-B2 Lubricating oils for automatic transmissions CHEVRON JAPAN LTD. (JP) 2020-03-31 US claimed
US-10260059-B2 Nitrilase from arabis alpina, its encoding gene, vector, recombinant bacterial strain and uses thereof ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2019-04-16 US claimed
US-20170355976-A1 NITRILASE FROM ARABIS ALPINA, ITS ENCODING GENE, VECTOR, RECOMBINANT BACTERIAL STRAIN AND USES THEREOF ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2017-12-14 US claimed
US-20170058274-A1 NITRILASE FROM ARABIS ALPINA, ITS ENCODING GENE, VECTOR, RECOMBINANT BACTERIAL STRAIN AND USES THEREOF ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2017-03-02 US claimed
EP-1163315-B1 COMPOSITIONS FOR PREPARING WATER-IN-OIL MICROEMULSIONS PALOX OFFSHORE S A L (LB) 2008-04-16 EP claimed
US-6716801-B2 Compositions and method for their preparation Abu-Jawdeh, Pauline (GB) 2004-04-06 US claimed
US-20030134755-A1 Compositions and a method for their preparation PALOX LTD (CY) 2003-07-17 US claimed
US-20020051801-A1 Small droplet size of the water phase of the water-in-oil emulsion; small droplet size imparts translucency, which negates the need for both corrosion inhibitors and bactericides; water in fuel emulsions ABU-JAWDEH PAULINE (GB) 2002-05-02 US claimed
EP-1163315-A1 COMPOSITIONS FOR PREPARING WATER-IN-OIL MICROEMULSIONS Abu-Jawdeh, Pauline (GB) 2001-12-19 EP claimed
WO-2000053699-A1 COMPOSITIONS FOR PREPARING WATER-IN-OIL MICROEMULSIONS THE BURWOOD CORPORATION LIMITED (GB) 2000-09-14 WO claimed
EP-0206748-B1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION CONTAINING THE SAME CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1992-09-02 EP claimed
EP-4214297-B1 ARYLOXY ALKYLAMINES AS FUEL ADDITIVES FOR REDUCING INJECTOR FOULING IN DIRECT INJECTION SPARK IGNITION GASOLINE ENGINES CHEVRON ORONITE CO (US) 2024-07-10 EP disclosed
US-20240026239-A1 ARYLOXY ALKYLAMINES AS FUEL ADDITIVES FOR REDUCING INJECTOR FOULING IN DIRECT INJECTION SPARK IGNITION GASOLINE ENGINE CHEVRON ORONITE COMPANY LLC (US) 2024-01-25 US disclosed
CN-114106787-B Cooling medium composition and preparation method thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
US-4173456-A Polyolefin/acylated poly(alkyleneamine) two component fuel additive E. I. DU PONT DE NEMOURS & CO. (US) 1979-11-06 US disclosed
US-4172855-A Lubricant ETHYL CORPORATION (US) 1979-10-30 US disclosed
US-4158633-A DIMETHYLHYDROCARBYLPHOSPHONATE OIL ADDITIVE TO LOWER FUEL CONSUMPTION EDWIN COOPER, INC. (US) 1979-06-19 US disclosed
US-4147640-A ADDITIVES MADE BY REACTING OLEFIN WITH SULFUR AND HYDROGEN SULFIDE, OXIDATION AND WEAR RESISTANCE EDWIN COOPER AND COMPANY LIMITED (GB) 1979-04-03 US disclosed