Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 4/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825527 | 0.91 | POLB (0.48) | POLB | |
| SCHEMBL9824930 | 0.82 | POLB (0.70) | POLBABCB1CYP3A4CYP2C9 | |
| SCHEMBL9825307 | 0.78 | HPGD (0.70) | POLBABCB1CYP3A4 | |
| SCHEMBL9714344 | 0.75 | POLB (0.70) | POLBHTTCYP3A4CYP2C9 | |
| SCHEMBL9714353 | 0.75 | POLB (0.70) | POLBHTTCYP3A4CYP2C9 | |
| SCHEMBL8773675 | 0.72 | POLB (0.70) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9714380 | 0.72 | CA1 (0.38) | HTTCYP3A4CYP2C9 | |
| SCHEMBL10721630 | 0.71 | HTT (0.61) | ABCB1HTT | |
| SCHEMBL9815860 | 0.70 | ABCB1 (0.45) | POLBABCB1 | |
| SCHEMBL9825310 | 0.69 | HPGD (0.70) | ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |