SCHEMBL9815860

SCHEMBL9815860

CC(C)(C)N(NC(=O)c1ccccc1I)C(=O)c1ccccn1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 3/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815861 0.90 ABCB1 (0.47) ABCB1
SCHEMBL9510595 0.85 ABCB1 (0.45) ABCB1POLB
SCHEMBL9815886 0.83 CTNNB1 (0.52) ABCB1POLB
SCHEMBL8173237 0.82 POLB (0.68) POLB
SCHEMBL9815835 0.81 ABCB1 (0.52) ABCB1
SCHEMBL9510944 0.81 KDM4E (0.49) ABCB1
SCHEMBL9824930 0.80 POLB (0.70) ABCB1POLB
SCHEMBL9815854 0.79 ABCB1 (0.58) ABCB1
SCHEMBL9815800 0.79 POLB (0.56) ABCB1POLB
SCHEMBL9815793 0.78 ABCB1 (0.62) ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253468-B1 SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-11-06 EP disclosed