Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742666 | 0.94 | PTPN1 (0.31) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11744557 | 0.94 | PTPN1 (0.31) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL9344144 | 0.90 | — | — | |
| SCHEMBL25612545 | 0.88 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1TDP1EPHX1 | |
| SCHEMBL4633450 | 0.88 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL4408566 | 0.88 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL31623378 | 0.87 | ALDH1A1 (0.33) | ALDH1A1TDP1EPHX1 | |
| SCHEMBL31623366 | 0.87 | ALDH1A1 (0.33) | ALDH1A1TDP1EPHX1 | |
| SCHEMBL31623372 | 0.87 | ALDH1A1 (0.33) | ALDH1A1TDP1EPHX1 | |
| SCHEMBL11373443 | 0.87 | ALDH1A1 (0.33) | MEN1KMT2AMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185359-B1 | OXETANONE | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-04 | — | — | EP | disclosed |
| EP-0185359-A2 | Oxetanone | F. HOFFMANN-LA ROCHE AG (CH) | 1986-06-25 | — | — | EP | disclosed |