Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934061 | 0.90 | TGM2 (0.49) | TGM2ITGB3ITGA2BSLC15A1ALPI | |
| SCHEMBL4934993 | 0.90 | TGM2 (0.49) | TGM2ITGB3ITGA2BSLC15A1ALPI | |
| SCHEMBL9825676 | 0.86 | TGM2 (0.47) | TGM2ITGB3ITGA2BSLC15A1ALPI | |
| SCHEMBL4950332 | 0.85 | TGM2 (0.47) | TGM2ITGB3ITGA2BSLC15A1ALPI | |
| SCHEMBL9826376 | 0.84 | TGM2 (0.41) | TGM2ALPIPKMPTGS1XIAP | |
| SCHEMBL9825692 | 0.83 | TGM2 (0.46) | TGM2 | |
| SCHEMBL4936405 | 0.83 | TGM2 (0.38) | TGM2ITGB3ITGA2BL3MBTL1SLC15A1 | |
| SCHEMBL9825346 | 0.83 | TGM2 (0.38) | TGM2ITGB3ITGA2BL3MBTL1SLC15A1 | |
| SCHEMBL4935929 | 0.83 | TGM2 (0.40) | TGM2MAPTTHRBPOLBALPI | |
| SCHEMBL9825788 | 0.82 | TGM2 (0.39) | TGM2L3MBTL1MAPTALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | claimed |