Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034511 | 0.84 | MIF (0.43) | MIFLMNAACACBACACAHTT | |
| SCHEMBL9826015 | 0.82 | MIF (0.42) | MIFLMNAACACBACACAHTT | |
| SCHEMBL12449472 | 0.80 | MIF (0.40) | MIFLMNAACACBACACAHTT | |
| SCHEMBL4610456 | 0.79 | MIF (0.40) | MIFLMNAACACBACACAHTT | |
| SCHEMBL9825478 | 0.79 | MIF (0.40) | MIFLMNAACACBACACAHTT | |
| SCHEMBL590406 | 0.75 | HCRTR2 (0.47) | HTTNPSR1DRD2EPHX1TDP1 | |
| SCHEMBL590405 | 0.75 | HCRTR2 (0.47) | HTTNPSR1DRD2EPHX1TDP1 | |
| SCHEMBL2750096 | 0.75 | HCRTR2 (0.47) | HTTNPSR1DRD2EPHX1TDP1 | |
| SCHEMBL28662054 | 0.72 | HCRTR2 (0.45) | HTTEPHX1TDP1HPGD | |
| SCHEMBL28662052 | 0.72 | HCRTR2 (0.45) | HTTEPHX1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | claimed |
| EP-0237082-A2 | 3,5-disubstituted 4,5-dihydroisoxazoles as transglutaminase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1987-09-16 | — | — | EP | claimed |