SCHEMBL9826164

SCHEMBL9826164

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ccccc2S(=O)(=O)NN(C)C)n1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.59
CDK1 P06493 1/20 0.57
MAPT P10636 3/20 0.48
TP53 P04637 1/20 0.48
GLA P06280 1/20 0.48
CYP1A2 P05177 1/20 0.46
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10616134 0.93 GAA (0.67) GAACDK1MAPTTP53GLA
SCHEMBL10508252 0.89 GAA (0.58) GAACDK1MAPTTP53GLA
SCHEMBL11086097 0.87 GAA (0.56) GAACDK1MAPTTP53GLA
SCHEMBL10736294 0.87 GAA (0.56) GAACDK1MAPTTP53GLA
SCHEMBL10616100 0.87 GAA (0.60) GAACDK1MAPTTP53GLA
SCHEMBL10339438 0.87 GAA (0.60) GAACDK1MAPTTP53GLA
SCHEMBL11092594 0.85 GAA (0.54) GAACDK1MAPTTP53GLA
SCHEMBL10884559 0.85 GAA (0.61) GAACDK1MAPTTP53GLA
SCHEMBL10509250 0.85 CDK1 (0.70) GAACDK1MAPTTP53GLA
SCHEMBL10568292 0.85 GAA (0.58) GAACDK1MAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192489-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-04-10 EP claimed
US-4662932-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-05 US claimed
EP-0192489-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-08-27 EP claimed
EP-0192489-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-04-10 EP disclosed
US-4718938-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-12 US disclosed
US-4718938-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-12 US disclosed
US-4662932-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-05 US disclosed
US-4662932-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-05 US disclosed
EP-0192489-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-08-27 EP disclosed