Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 14/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932001 | 0.88 | TGM2 (0.57) | TGM2ITGB3ITGA2BCYP1A2 | |
| SCHEMBL4935966 | 0.86 | TGM2 (0.55) | TGM2ITGB3ITGA2BCYP1A2 | |
| SCHEMBL9825654 | 0.85 | TGM2 (0.62) | TGM2ITGB3ITGA2BCYP1A2ITGAV | |
| SCHEMBL9825490 | 0.83 | TGM2 (0.86) | TGM2 | |
| SCHEMBL4657328 | 0.82 | TGM2 (0.58) | TGM2ITGB3ITGA2BCYP1A2ITGAV | |
| SCHEMBL4598615 | 0.80 | TGM2 (0.51) | TGM2 | |
| SCHEMBL9825955 | 0.79 | TGM2 (0.46) | TGM2ITGB3ITGA2BCYP1A2ITGAV | |
| SCHEMBL4597992 | 0.78 | TGM2 (0.56) | TGM2 | |
| SCHEMBL9825089 | 0.78 | TGM2 (0.46) | TGM2ITGB3ITGA2BCYP1A2ITGAV | |
| SCHEMBL1091124 | 0.77 | TGM2 (0.93) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | claimed |
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | disclosed |