SCHEMBL9826324

SCHEMBL9826324

CCOC(=O)c1oc(C(=O)OCC)c(O)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 1/20 0.49
CA12 O43570 4/20 0.45
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
CA7 P43166 4/20 0.45
CA9 Q16790 4/20 0.45
CA14 Q9ULX7 4/20 0.45
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
KDM4E B2RXH2 1/20 0.45
AHR P35869 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8598477 0.90 MAPT (0.45) MAPTNPC1RAB9ACA12CA1
SCHEMBL16272967 0.77 NPC1 (0.45) MAPTNPC1RAB9ACA12CA1
SCHEMBL96205 0.77 HPGD (0.50) MAPTNPC1RAB9ACA12CA1
SCHEMBL4775716 0.75 KDM4E (0.71) MAPTNPC1RAB9AKDM4EAHR
SCHEMBL11701604 0.74 ALDH1A1 (0.58) MAPTNPC1RAB9AKDM4EAHR
SCHEMBL9826319 0.74 KDM4E (0.40) MAPTNPC1RAB9ACA12CA1
SCHEMBL96204 0.74 HPGD (0.43) MAPTNPC1RAB9ACA12CA1
SCHEMBL9826102 0.74 CA12 (0.51) MAPTNPC1RAB9ACA12CA1
SCHEMBL11453281 0.73 CELA1 (0.46) MAPTCA12CA1CA2CA7
Potassium SCHEMBL7063557 0.71 CELA1 (0.44) MAPTCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114521553-B Special antifeedant for preventing and controlling insect gall thrips on ficus plants 福建省农业科学院植物保护研究所 2023-04-25 CN claimed
CN-114521553-A A special food refusal for preventing and controlling insect thrips on Ficus plant 福建省农业科学院植物保护研究所 2022-05-24 CN claimed
CN-114521553-B Special antifeedant for preventing and controlling insect gall thrips on ficus plants 福建省农业科学院植物保护研究所 2023-04-25 CN disclosed
CN-114521553-B Special antifeedant for preventing and controlling insect gall thrips on ficus plants 福建省农业科学院植物保护研究所 2023-04-25 CN disclosed
CN-114521553-A A special food refusal for preventing and controlling insect thrips on Ficus plant 福建省农业科学院植物保护研究所 2022-05-24 CN disclosed
CN-114521553-A A special food refusal for preventing and controlling insect thrips on Ficus plant 福建省农业科学院植物保护研究所 2022-05-24 CN disclosed
EP-0249236-B1 N-1H-TETRAZOL-5-YL-(5-RING)-CARBOXAMIDE-DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE, AND THE USE THEREOF WARNER-LAMBERT COMPANY (US) 1991-04-24 EP disclosed
US-4824958-A Process for the preparation of n-1H-tetrazol-5-yl-2-pyrrole carboxamides WARNER-LAMBERT COMPANY (US) 1989-04-25 US disclosed
US-4748183-A N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof WARNER-LAMBERT COMPANY (US) 1988-05-31 US disclosed
EP-0249236-A1 N-1H-Tetrazol-5-yl-(5-Ring)-carboxamide-derivatives, a process for their manufacture, and the use thereof WARNER-LAMBERT COMPANY (US) 1987-12-16 EP disclosed