Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.62 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29196250 | 0.89 | SMN1; SMN2 (0.52) | CYP4F2CYP4A11SMN1; SMN2LMNAGAA | |
| SCHEMBL9828113 | 0.89 | CYP4F2 (0.51) | CYP4F2CYP4A11SMN1; SMN2LMNAGAA | |
| SCHEMBL1515826 | 0.88 | CYP4F2 (0.62) | CYP4F2CYP4A11SMN1; SMN2LMNAGAA | |
| SCHEMBL4052165 | 0.88 | CYP4F2 (0.67) | CYP4F2CYP4A11SMN1; SMN2LMNAGAA | |
| SCHEMBL2772618 | 0.86 | HTT (0.48) | CYP4F2CYP4A11SMN1; SMN2LMNAGAA | |
| SCHEMBL9417955 | 0.85 | CYP4F2 (0.59) | CYP4F2CYP4A11SMN1; SMN2LMNAGAA | |
| SCHEMBL29196231 | 0.85 | PPARG (0.56) | SMN1; SMN2LMNAGAATDP1HSD17B2 | |
| SCHEMBL7410301 | 0.83 | CYP4F2 (0.68) | CYP4F2CYP4A11SMN1; SMN2LMNAGAA | |
| SCHEMBL11012998 | 0.82 | TAAR1 (0.56) | SMN1; SMN2LMNAGAATDP1HSD17B2 | |
| SCHEMBL29196254 | 0.82 | SMN1; SMN2 (0.47) | CYP4F2CYP4A11SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150892-B1 | SUBSTITUTED ALKYLIDENE IMIDAZOLES | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4837333-A | SELECTIVE INHIBITOR OF THROMBOXANE SYNTHETASE ENZYME | G. D. SEARLE & CO. (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0150892-A2 | Substituted alkylidene imidazoles | G.D. Searle & Co. (US) | 1985-08-07 | — | — | EP | disclosed |