Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826415 | 0.89 | CYP4F2 (0.62) | CYP4F2CYP4A11TSHRMAPTKMT2A | |
| SCHEMBL9827680 | 0.84 | CYP4F2 (0.62) | CYP4F2CYP4A11TSHRMAPTALOX15 | |
| SCHEMBL29196250 | 0.79 | SMN1; SMN2 (0.52) | CYP4F2CYP4A11TSHRMAPTKMT2A | |
| SCHEMBL1515826 | 0.78 | CYP4F2 (0.62) | CYP4F2CYP4A11TSHRMAPTKMT2A | |
| SCHEMBL4052165 | 0.78 | CYP4F2 (0.67) | CYP4F2CYP4A11TSHRMAPTRAB9A | |
| SCHEMBL2772618 | 0.76 | HTT (0.48) | CYP4F2CYP4A11TSHRMAPTKMT2A | |
| SCHEMBL9417955 | 0.76 | CYP4F2 (0.59) | CYP4F2CYP4A11TSHRMAPTKMT2A | |
| SCHEMBL29196231 | 0.75 | PPARG (0.56) | TSHRMAPTKMT2ARAB9ANPC1 | |
| Bromide SCHEMBL9827145 | 0.75 | TSHR (0.44) | TSHRMAPTKMT2AALOX15MEN1 | |
| SCHEMBL506455 | 0.74 | PPARG (0.61) | CYP4F2CYP4A11TSHRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150892-B1 | SUBSTITUTED ALKYLIDENE IMIDAZOLES | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4837333-A | SELECTIVE INHIBITOR OF THROMBOXANE SYNTHETASE ENZYME | G. D. SEARLE & CO. (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0150892-A2 | Substituted alkylidene imidazoles | G.D. Searle & Co. (US) | 1985-08-07 | — | — | EP | disclosed |