SCHEMBL9826417

SCHEMBL9826417

C#CCN1CC(C)(C)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 1/20 0.41
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14734296 0.75 PLA2G7 (0.45) PLA2G7
SCHEMBL11795396 0.75 SMN1; SMN2 (0.39)
SCHEMBL9409691 0.74 CHRM2 (0.51)
SCHEMBL2713645 0.74 PLA2G7 (0.44) PLA2G7
SCHEMBL7336615 0.71 PLA2G7 (0.49) PLA2G7
SCHEMBL5148891 0.71 PLA2G7 (0.49) PLA2G7
SCHEMBL2715902 0.71 PLA2G7 (0.49) PLA2G7
SCHEMBL2714244 0.71 PLA2G7 (0.49) PLA2G7
SCHEMBL2185862 0.68 PLA2G7 (0.47) PLA2G7
SCHEMBL13293918 0.68 CHRM3 (0.56) PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0440670-A1 HETEROCYCLIC ACETYLENIC AMINES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY. UPJOHN CO (US) 1991-08-14 EP disclosed