Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720710 | 0.89 | CYP11B1 (0.54) | CYP11B1CYP11B2POLBCYP19A1QPCT | |
| SCHEMBL9720833 | 0.86 | CYP11B1 (0.55) | CYP11B1CYP11B2POLBCYP19A1QPCT | |
| SCHEMBL15720237 | 0.82 | CYP11B1 (0.65) | CYP11B1CYP11B2POLBCYP19A1TBXAS1 | |
| SCHEMBL11624547 | 0.81 | CYP11B1 (0.57) | CYP11B1CYP11B2POLBCYP19A1TBXAS1 | |
| SCHEMBL11620329 | 0.81 | CYP11B1 (0.68) | CYP11B1CYP11B2POLBCYP19A1TBXAS1 | |
| SCHEMBL5545363 | 0.77 | CYP11B1 (0.78) | CYP11B1CYP11B2POLBCYP19A1TBXAS1 | |
| SCHEMBL9720848 | 0.77 | CYP11B1 (0.59) | CYP11B1CYP11B2POLBCYP19A1QPCT | |
| SCHEMBL15179016 | 0.77 | CYP11B1 (0.76) | CYP11B1CYP11B2POLBCYP19A1TBXAS1 | |
| SCHEMBL30523909 | 0.77 | CYP11B1 (0.76) | CYP11B1CYP11B2POLBCYP19A1TBXAS1 | |
| SCHEMBL30523908 | 0.77 | CYP11B1 (0.76) | CYP11B1CYP11B2POLBCYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | disclosed |
| EP-0352352-A1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1990-01-31 | — | — | EP | disclosed |