Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.55 |
| ▸ | QPCT | Q16769 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720837 | 0.90 | CYP11B1 (0.57) | CYP11B1CYP11B2QPCTPOLBPDE4B | |
| SCHEMBL9720710 | 0.88 | CYP11B1 (0.54) | CYP11B1CYP11B2QPCTPOLBCYP19A1 | |
| SCHEMBL9826451 | 0.86 | CYP11B1 (0.57) | CYP11B1CYP11B2QPCTPOLBCYP19A1 | |
| SCHEMBL9720811 | 0.85 | CYP11B1 (0.53) | CYP11B1CYP11B2QPCTPOLBPDE4B | |
| SCHEMBL5545363 | 0.79 | CYP11B1 (0.78) | CYP11B1CYP11B2QPCTPOLBCYP19A1 | |
| SCHEMBL9720848 | 0.78 | CYP11B1 (0.59) | CYP11B1CYP11B2QPCTPOLBCYP19A1 | |
| SCHEMBL15720237 | 0.75 | CYP11B1 (0.65) | CYP11B1CYP11B2QPCTPOLBCYP19A1 | |
| SCHEMBL9720792 | 0.74 | PDCD1 (0.42) | — | |
| SCHEMBL9720745 | 0.74 | DHODH (0.38) | CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL906443 | 0.72 | CYP11B1 (1.00) | CYP11B1CYP11B2QPCTPOLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149707-A | 1-((2-FLUOROPHENYL)(4-FLUOROPHENYL)PHENYLMETHYL)-1H-IMIDAZOLE USEFUL AS ANTIFUNGAL AGENT | J. URIACH & CIA, S.A. (ES) | 1992-09-22 | — | — | US | disclosed |
| EP-0352352-B1 | 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole | J. URIACH & CIA. S.A. (ES) | 1991-10-16 | — | — | EP | disclosed |