Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825074 | 0.91 | PTPN11 (0.33) | ALDH1A1LMNAL3MBTL1CASRHTT | |
| SCHEMBL9825608 | 0.91 | PTPN11 (0.33) | ALDH1A1LMNAL3MBTL1CASRHTT | |
| SCHEMBL9825718 | 0.91 | PTPN11 (0.33) | ALDH1A1LMNAL3MBTL1CASRHTT | |
| SCHEMBL9825966 | 0.86 | CASR (0.36) | ALDH1A1LMNAL3MBTL1CASRHTT | |
| SCHEMBL9825138 | 0.80 | NEK1 (0.40) | — | |
| SCHEMBL9824980 | 0.79 | CASR (0.39) | ALDH1A1LMNAL3MBTL1CASRHTT | |
| SCHEMBL9826044 | 0.77 | NCF1 (0.32) | HTTSMN1; SMN2PPARGPPARA | |
| SCHEMBL9825183 | 0.76 | CTSA (0.35) | ALDH1A1LMNAL3MBTL1CASRHTT | |
| SCHEMBL9826610 | 0.75 | CASR (0.38) | ALDH1A1LMNAL3MBTL1CASRHTT | |
| SCHEMBL9825456 | 0.74 | CTSA (0.33) | ALDH1A1LMNAL3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |