SCHEMBL9826673

SCHEMBL9826673

CCNc1cc2cc(Br)ccc2o1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 9/20 0.45
CA2 P00918 9/20 0.45
CA9 Q16790 9/20 0.45
CA1 P00915 8/20 0.45
CYP2A6 P11509 1/20 0.45
PIM1 P11309 1/20 0.44
USP2 O75604 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HTT P42858 1/20 0.43
MAOA P21397 1/20 0.43
CYP19A1 P11511 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GPR35 Q9HC97 1/20 0.41
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
ADAM17 P78536 1/20 0.40
ALDH2 P05091 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9826946 0.86 APP (0.38) CA12CA2CA9CA1CYP2A6
SCHEMBL19187891 0.84 CA12 (0.41) CA12CA2CA9CA1CYP2A6
SCHEMBL9826455 0.79 CA12 (0.40) CA12CA2CA9CA1MAOA
SCHEMBL9826008 0.79 MAOB (0.46) CA12CA2CA9CA1ALDH1A1
Hydrochloric Acid SCHEMBL10458744 0.78 MAOB (0.45) CA12CA2CA9CA1ALDH1A1
SCHEMBL9826735 0.77 TAS1R3 (0.52) CA12CA2CA9CA1CYP2A6
SCHEMBL140394 0.77 NPC1 (0.51) CYP2A6ALDH1A1MAOANPC1RAB9A
Hydrochloric Acid SCHEMBL10458713 0.76 TAS1R3 (0.51) CA12CA2CA9CA1CYP2A6
SCHEMBL9827183 0.76 CYP1A2 (0.45) CA12CA9CA1ALDH1A1MAOA
Hydrochloric Acid SCHEMBL9826526 0.75 NPC1 (0.50) ALDH1A1MAOANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0283522-B1 TRIAZINE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING SAME AS EFFECTIVE INGREDIENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-02-27 EP disclosed
US-4932998-A LOW PHYTOTOXICITY FOR PADDY RICE PLANTS IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-06-12 US disclosed
EP-0283522-A1 TRIAZINE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING SAME AS EFFECTIVE INGREDIENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-09-28 EP disclosed