Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 13/20 | 0.70 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364812 | 0.79 | DAO (0.70) | DAOKDM4ETSHRHPGD | |
| SCHEMBL27477952 | 0.78 | DAO (0.50) | DAODDOKDM4EPDE7ATSHR | |
| SCHEMBL7349965 | 0.71 | DAO (0.66) | DAOKDM4EPOLBHPGD | |
| SCHEMBL9362601 | 0.70 | MCL1 (0.41) | KDM4EHPGD | |
| SCHEMBL256746 | 0.69 | DAO (0.66) | DAODDOLMNA | |
| SCHEMBL30273105 | 0.69 | DAO (0.47) | DAODDOKDM4ETSHRLMNA | |
| SCHEMBL9362567 | 0.69 | CASP6 (0.40) | DAOKDM4EPDE7A | |
| SCHEMBL16310134 | 0.68 | DAO (0.64) | DAODDOKDM4E | |
| SCHEMBL9364622 | 0.68 | GRIN2D (0.58) | DAO | |
| SCHEMBL30577501 | 0.68 | DAO (0.46) | DAODDOKDM4EPDE7ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |