SCHEMBL9826985

SCHEMBL9826985

CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1C=NOc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 1/20 0.40
TTR P02766 1/20 0.40
PPOX P50336 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
EGFR P00533 4/20 0.40
ERBB2 P04626 4/20 0.40
HTR2A P28223 4/20 0.39
SLC6A4 P31645 4/20 0.39
KCNH2 Q12809 4/20 0.39
ERBB3 P21860 2/20 0.39
ERBB4 Q15303 2/20 0.39
PPARG P37231 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
PPARD Q03181 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9826979 1.00 FFAR1 (0.43) FFAR1L3MBTL1LMNAMAPTATM
SCHEMBL9827171 0.89 L3MBTL1 (0.45) FFAR1L3MBTL1LMNAMAPTATM
SCHEMBL9827166 0.89 L3MBTL1 (0.45) FFAR1L3MBTL1LMNAMAPTATM
SCHEMBL9827390 0.85 HPGD (0.48) FFAR1L3MBTL1LMNAMAPTATM
SCHEMBL9827396 0.85 HPGD (0.48) FFAR1L3MBTL1LMNAMAPTATM
SCHEMBL9827984 0.83 FFAR1 (0.46) FFAR1MAPTMEN1TTRPPOX
SCHEMBL9827982 0.83 FFAR1 (0.46) FFAR1MAPTMEN1TTRPPOX
SCHEMBL9827997 0.82 FFAR1 (0.48) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9827993 0.82 FFAR1 (0.48) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9827058 0.82 FFAR1 (0.48) FFAR1L3MBTL1LMNAMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442172-A1 Oxime derivatives and Herbicides containing the same as an active ingredient TEIJIN LIMITED (JP) 1991-08-21 EP disclosed
EP-0433451-A1 OXIME DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS AN ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1991-06-26 EP disclosed
WO-1990001874-A1 OXIME DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS AN ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1990-03-08 WO disclosed