Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827268 | 1.00 | HSD17B10 (0.43) | HSD17B10LMNAHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9827478 | 0.81 | CES1 (0.42) | HSD17B10LMNAHPGDALDH1A1CYP1A2 | |
| SCHEMBL10658365 | 0.72 | CES1 (0.51) | ALDH1A1HTR1ACES1HTT | |
| SCHEMBL9827759 | 0.67 | HTR1A (0.41) | HTR1AHTR6 | |
| SCHEMBL9828460 | 0.64 | HTR1A (0.42) | HTR1AHTR6 | |
| SCHEMBL9828705 | 0.64 | HTR1A (0.41) | HTR1AHTR6 | |
| SCHEMBL2733083 | 0.63 | HPGD (0.77) | HSD17B10LMNAHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL1201521 | 0.63 | HPGD (0.77) | HSD17B10LMNAHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL1201517 | 0.63 | HPGD (0.77) | HSD17B10LMNAHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL29417938 | 0.63 | HPGD (0.77) | HSD17B10LMNAHPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239129-B1 | HYDROQUINOLINE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |
| US-4963566-A | ANTIULCER AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0239129-A2 | Hydroquinoline compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |