Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 12/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGAV | P06756 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826332 | 0.93 | TGM2 (0.75) | TGM2ITGB3ITGAVITGA2B | |
| SCHEMBL3015992 | 0.88 | TGM2 (0.93) | TGM2 | |
| SCHEMBL1091157 | 0.88 | TGM2 (0.93) | TGM2 | |
| SCHEMBL1091121 | 0.88 | TGM2 (0.93) | TGM2 | |
| SCHEMBL1091124 | 0.88 | TGM2 (0.93) | TGM2 | |
| SCHEMBL1091158 | 0.88 | TGM2 (0.93) | TGM2 | |
| SCHEMBL9825176 | 0.87 | TGM2 (0.65) | TGM2ITGB3ITGAVITGA2B | |
| SCHEMBL9826016 | 0.86 | TGM2 (0.72) | TGM2 | |
| SCHEMBL9825490 | 0.85 | TGM2 (0.86) | TGM2 | |
| SCHEMBL13934076 | 0.84 | TGM2 (1.00) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | claimed |